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Gamma-secretase
Neuroscience
Gamma-secretase
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Aβ42-IN-2
catalog no : M37643
cas no: 1914989-80-2
Aβ42-IN-2, a γ-secretase modulator with an IC50 of 6.5 nM for Αβ42, can be used for Alzheimer's disease research .
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5β-Cholanic acid
catalog no : M37605
cas no: 546-18-9
5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.
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Enoticumab
catalog no : M37268
cas no: 1192578-27-0
Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody with anticancer activity that inhibits the growth of cancer cells.Enoticumab binds human Dll4 and disrupts Notch-mediated signaling.
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Demcizumab
catalog no : M36721
cas no: 1243262-17-0
Demcizumab (OMP 21M18) is an anti-DLL4 monoclonal antibody and a potent Notch pathway inhibitor, demonstrating efficacy in various cancer models both as a monotherapy and in conjunction with chemotherapy agents.
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Brontictuzumab
catalog no : M36719
cas no: 1447814-75-6
Brontictuzumab (OMP 52M5) is a monoclonal antibody that targets Notch1 and inhibits activation of the pathway.