Molnupiravir

CAS No. 2492423-29-5

Molnupiravir( —— )

Catalog No. M35495 CAS No. 2492423-29-5

Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 58 In Stock
5MG 32 In Stock
10MG 52 In Stock
25MG 68 In Stock
50MG 113 In Stock
100MG 183 In Stock
200MG 346 In Stock
500MG 733 In Stock
1G 1004 In Stock

Biological Information

  • Product Name
    Molnupiravir
  • Note
    Research use only, not for human use.
  • Brief Description
    Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.
  • Description
    Molnupiravir (EIDD-2801) is an orally bioavailable proagent of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza.
  • In Vitro
    ——
  • In Vivo
    Animal Model:C57BL/6 mice (intranasal infection with SARS-CoV)Dosage:50, 150, 500 mg/kg Administration:Oral; every 12 hours for 3 days Result:Body weight loss is significantly diminished or prevented.Animal Model: Ca/09-infected female ferrets Dosage:7 mg/kg Administration:Oral; twice daily for 3.5 days Result:Shed virus load and duration of fever were significantly reduced.
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Influenza Virus
  • Recptor
    Influenza Virus | SARS-CoV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2492423-29-5
  • Formula Weight
    329.31
  • Molecular Formula
    C13H19N3O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (151.83 mM; Ultrasonic )H2O : 12.5 mg/mL (37.96 mM; Ultrasonic)
  • SMILES
    CC(C)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc\c(=N/O)[nH]c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sheahan TP, et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Sci Transl Med. 2020 Apr 6. pii: eabb5883.?
molnova catalog
related products
  • SP187

    SP187 (MON-DNJ) is a host-targeted iminosugar. It has anti-filovirus infection activity.SP187 is used for therapeutic use against influenza and dengue viruses.

  • IHVR-17028

    IHVR-17028 is a potent broad-spectrum ERα-glucosidase I (α-glucosidase? I) inhibitor with IC50 of 0.24 μM and antiviral activity. IHVR-17028 inhibited BVDV, TCRV and DENV, and EC50 values were 0.4 μM, 0.26 μM and 0.3 μM, respectively.

  • Platyphyllonol

    Platyphyllonol-5-xylopyranoside is moderately active against KBNP-0028 (H9N2) avian influenza virus as compared with zanamivir.