RO7185876
CAS No. 2226038-71-5
RO7185876( —— )
Catalog No. M35141 CAS No. 2226038-71-5
RO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer's disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 686 | In Stock |
|
| 10MG | 938 | In Stock |
|
| 25MG | 1444 | In Stock |
|
| 50MG | 1841 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameRO7185876
-
NoteResearch use only, not for human use.
-
Brief DescriptionRO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer's disease.
-
DescriptionRO7185876 is a potent and selective gamma secretase modulator as a potential research for Alzheimer's disease.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayNeuroscience
-
TargetGamma-secretase
-
RecptorGamma-secretase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2226038-71-5
-
Formula Weight483.532
-
Molecular FormulaC25H28F3N7
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESN(C=1N=C2[C@@H](CCCCN2N1)C3=C(F)C(F)=C(F)C=C3)[C@H]4[C@@]5(CN(C[C@]4(CC5)[H])C=6C=C(C)N=CN6)[H]
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ratni H, et al. Discovery of RO7185876, a Highly Potent γ-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer's Disease. ACS Med Chem Lett. 2020 Apr 27;11(6):1257-1268. ?
molnova catalog
related products
-
(20S)-Protopanaxadio...
(20S)-Protopanaxadiol (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin.
-
BI-1408
BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).
-
Gossypolone
Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.
Cart
sales@molnova.com