RO7185876

CAS No. 2226038-71-5

RO7185876( —— )

Catalog No. M35141 CAS No. 2226038-71-5

RO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    RO7185876
  • Note
    Research use only, not for human use.
  • Brief Description
    RO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer's disease.
  • Description
    RO7185876 is a potent and selective gamma secretase modulator as a potential research for Alzheimer's disease.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Neuroscience
  • Target
    Gamma-secretase
  • Recptor
    Gamma-secretase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2226038-71-5
  • Formula Weight
    483.532
  • Molecular Formula
    C25H28F3N7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C=1N=C2[C@@H](CCCCN2N1)C3=C(F)C(F)=C(F)C=C3)[C@H]4[C@@]5(CN(C[C@]4(CC5)[H])C=6C=C(C)N=CN6)[H]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ratni H, et al. Discovery of RO7185876, a Highly Potent γ-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer's Disease. ACS Med Chem Lett. 2020 Apr 27;11(6):1257-1268. ?
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