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Mc-VC-PAB-SN38
CAS No. 1801838-28-7
Mc-VC-PAB-SN38( —— )
Catalog No. M35101 CAS No. 1801838-28-7
Mc-VC-PAB-SN38 consists of a cleavable ADC linker (Mc-VC-PAB) and SN38, which is part of an antibody-coupled reactive molecule commonly used to synthesize antibody-coupled reactive molecules (ADCs) that target sites of action.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 293 | Get Quote |
|
| 5MG | 464 | Get Quote |
|
| 10MG | 700 | Get Quote |
|
| 25MG | 1095 | Get Quote |
|
| 50MG | 1592 | Get Quote |
|
| 100MG | 2124 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMc-VC-PAB-SN38
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NoteResearch use only, not for human use.
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Brief DescriptionMc-VC-PAB-SN38 consists of a cleavable ADC linker (Mc-VC-PAB) and SN38, which is part of an antibody-coupled reactive molecule commonly used to synthesize antibody-coupled reactive molecules (ADCs) that target sites of action.
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DescriptionMc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAntibody Drug Conjugates (ADC)
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TargetDrug-Linker Conjugates
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RecptorDrug-Linker Conjugates for ADC
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Research Area——
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Indication——
Chemical Information
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CAS Number1801838-28-7
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Formula Weight991.05
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Molecular FormulaC51H58N8O13
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 28.57 mg/mL (28.83 mM; Ultrasonic )
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SMILESCCc1c2Cn3c(cc4c(COC(=O)[C@@]4(CC)OC(=O)OCc4ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN5C(=O)C=CC5=O)C(C)C)cc4)c3=O)-c2nc2ccc(O)cc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.?
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