Leukotriene D4( —— )

Catalog No. M35009 CAS No. 73836-78-9

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HNMR

HPLC

MSDS

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Product Name

Leukotriene D4
Note

Research use only, not for human use.
Brief Description

Leukotriene D4 (LTD4) is a potent pro-inflammatory mediator formed from arachidonic acid, a bronchoconstrictor, and induces osteoclast senescence.
Description

Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability.
In Vitro

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In Vivo

Leukotriene D4 (1.5, 3, 6, 12, 24 μg/paw; injected intradermally) causes edema and increases capillary permeability in a dose-related manner in mouse.Animal Model:21-24 g, Balb/c male mice Dosage:1.5, 3, 6, 12, 24 μg/paw Administration:Injected intradermally (10 μL was injected into the left hind paw)Result:Caused significant edematous response and dye extravasation at doses of 1.5-6 ~g/paw.
Synonyms

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Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Endogenous Metabolite | Drug Metabolite
Research Area

——
Indication

——

CAS Number

73836-78-9
Formula Weight

496.66
Molecular Formula

C25H40N2O6S
Purity

>98% (HPLC)
Solubility

——
SMILES

[C@H](SC[C@@H](C(NCC(O)=O)=O)N)([C@H](CCCC(O)=O)O)/C=C/C=C/C=C\C/C=C\CCCCC
Chemical Name

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1. Smith LJ, et al. The effect of inhaled leukotriene D4 in humans. Am Rev Respir Dis. 1985 Mar;131(3):368-72.?

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