GIP (3-42), human

CAS No. 1802086-25-4

GIP (3-42), human( —— )

Catalog No. M34964 CAS No. 1802086-25-4

GIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) is a peptide that acts as a glucose-dependent proinsulinotropic polypeptide (GIP) receptor antagonist and regulates insulin secretion and the metabolic effects of GIP in vivo, which can be used to study type 2 diabetes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 463 In Stock
10MG 661 In Stock
25MG 1036 In Stock
50MG 1386 In Stock
100MG 1841 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GIP (3-42), human
  • Note
    Research use only, not for human use.
  • Brief Description
    GIP (3-42), human (Gastric Inhibitory Polypeptide (3-42) (human)) is a peptide that acts as a glucose-dependent proinsulinotropic polypeptide (GIP) receptor antagonist and regulates insulin secretion and the metabolic effects of GIP in vivo, which can be used to study type 2 diabetes.
  • Description
    GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo.
  • In Vitro
    The incretin hormone GIP is rapidly degraded in the circulation by dipeptidyl peptidase IV (DPP IV) forming the N-terminally truncated peptide GIP(3-42).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    IGF-1R
  • Recptor
    IGF-1R
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1802086-25-4
  • Formula Weight
    4749.35
  • Molecular Formula
    C214H324N58O63S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (21.06 mM; Ultrasonic )H2O : 50 mg/mL (10.53 mM; Ultrasonic)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. V A Gault, et al. Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP(3-42), is a GIP receptor antagonist in vivo. J Endocrinol. 2002 Nov;175(2):525-33.?
molnova catalog
related products
  • GSK1904529A

    GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM.

  • NT157

    NT157 is a small molecule tyrphostin targeting IRS protein and has the potential to inhibit IGF-1R and STAT3 signaling pathways in TME cancer cells and stromal cells, resulting in decreased cancer cell survival.

  • LMPTP INHIBITOR 1 hy...

    LMPTP INHIBITOR 1 is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM LMPTP-A.