Norcholic Acid( —— )

Catalog No. M34922 CAS No. 60696-62-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Norcholic Acid
Note

Research use only, not for human use.
Brief Description

Norcholic Acid (Nor Cholic Acid) is a bile acid that promotes tumor progression and immune escape by modulating the farnesol X receptor in hepatocellular carcinoma.
Description

Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine.
In Vitro

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In Vivo

Animal Model:Male Wistar rats (100~150g)Dosage:6.4 g/L Administration:P.o.Result:Shows that averaging 40 % of the administered radioactivity was recovered from the feces during the first 24 hours.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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CAS Number

60696-62-0
Formula Weight

394.54
Molecular Formula

C23H38O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (253.46 mM; Ultrasonic )
SMILES

[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CC(O)=O
Chemical Name

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1. Nakatomi F, et al. Intestinal absorption and metabolism of norcholic acid in rats. J Pharmacobiodyn. 1985;8(7):557-563.?

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