Cart
sales@molnova.com
Leu-Leu-ome hydrochloride
CAS No. 6491-83-4
Leu-Leu-ome hydrochloride( —— )
Catalog No. M20979 CAS No. 6491-83-4
Leu-Leu-ome hydrochloride is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 43 | In Stock |
|
| 100MG | 38 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLeu-Leu-ome hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionLeu-Leu-ome hydrochloride is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes.
-
DescriptionLeu-Leu-ome hydrochloride is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes.
-
In VitroL-Leucyl-L-Leucine methyl ester (1 mM; 0.5-2 h) enhances LRRK2-mediated Rab10 and Rab12 phosphorylation in MEFs and A549 cells.L-Leucyl-L-Leucine methyl ester (10-250 μM; 15 min) is converted to a CCI3COOH-insoluble product by CD4- lymphocytes.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number6491-83-4
-
Formula Weight294.81
-
Molecular FormulaC13H27ClN2O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (847.98 mM)
-
SMILESCOC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C.Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Giusti P Skaper S D Marinelli C et al. Astrocyte-Microglia Cooperation in the Expression of a Pro-Inflammatory Phenotype[J]. CNS & Neurological Disorders - Drug Targets (Formerly Current Drug Targets 2013 12(5):-.
molnova catalog
related products
-
SIVmac251 (gp140) Fr...
SIVmac251 (gp140) Fragment (171-190) [Cys]
-
3,5-Dimethoxy-1-[(6-...
3,5-Dimethoxy-1-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]-9H-xanthen-9-one
-
FIDAS-5
FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding.?FIDAS-5 has anticancer activities.?FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM.FIDAS-5 induces the expression of cell cycle inhibitor, p21WAF1/CIP1. FIDAS-5 (3 μM; 36 h) treatment reduces the levels of both S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in LS174T cells.FIDAS-5 (3 μM; 7 days; LS174T cells) treatment significantly inhibits the proliferation of LS174T cells.
