Platyconic acid A

Research use only, not for human use.

Platyconic Acid A, derived from changkil saponins extracted from platycodon grandiflorum, is a potent compound employed for studying the mitigation of airway inflammation.

Platyconic Acid A, derived from changkil saponins extracted from platycodon grandiflorum, is a potent compound employed for studying the mitigation of airway inflammation.

Platyconic Acid A (0.5~2 μM; 30 minutes; A549 cells) inhibits PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner.Platyconic Acid A (0.5~2 μM; 24 hours; A549 cells) decreases PMA-increased MUC5AC mRNA expression in a concentration-dependent manner. Western Blot Analysis Cell Line:A549 cells Concentration:0.5~2 μM Incubation Time:30 minutes Result:Inhibited PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner.RT-PCR Cell Line:A549 cells Concentration:0.5~2 μM Incubation Time:24 hours Result:Decreased PMA-increased MUC5AC mRNA expression in a concentration-dependent manner.

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Others

Other Targets

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68051-23-0

1239.3

C57H90O29

>98% (HPLC)

In Vitro:?H2O : 25 mg/mL (20.17 mM助)

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(-20℃)

With Ice Pack

≥ 2 years