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AMP-Deoxynojirimycin

CAS No. 216758-20-2

AMP-Deoxynojirimycin( —— )

Catalog No. M34776 CAS No. 216758-20-2

AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and GCase 2, as well as GlcCer biosynthesis, and is utilized in the study of Parkinson's disease and diabetes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 560 In Stock
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50MG 1172 In Stock
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Biological Information

  • Product Name
    AMP-Deoxynojirimycin
  • Note
    Research use only, not for human use.
  • Brief Description
    AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and GCase 2, as well as GlcCer biosynthesis, and is utilized in the study of Parkinson's disease and diabetes.
  • Description
    AMP-Deoxynojirimycin (AMP-DNM) is a potent ceramide glucosyltransferase and GCase 2 inhibitor. AMP-Deoxynojirimycin also is a GlcCer biosynthesis inhibitor.
  • In Vitro
    AMP-Deoxynojirimycin (10 μM) significantly blocks the leucine and C17ISO-induced P70S6K phosphorylation in 3T3-L1 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Transferase
  • Recptor
    Transferase | Glucosidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    216758-20-2
  • Formula Weight
    397.55
  • Molecular Formula
    C22H39NO5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(OCCCCCN1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1)C23CC4CC(C2)CC(C3)C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhu M, et al. Monomethyl branched-chain fatty acid mediates amino acid sensing upstream of mTORC1. Dev Cell. 2021 Oct 11;56(19):2692-2702.e5.?
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