5,6-trans-Vitamin D3

CAS No. 22350-41-0

5,6-trans-Vitamin D3( —— )

Catalog No. M34765 CAS No. 22350-41-0

5,6-trans-Vitamin D3(5,6-trans-Cholecalciferol) is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 188 In Stock
10MG 322 In Stock
25MG 538 In Stock
50MG 736 In Stock
100MG 1014 In Stock
200MG Get Quote In Stock
500MG 2037 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    5,6-trans-Vitamin D3
  • Note
    Research use only, not for human use.
  • Brief Description
    5,6-trans-Vitamin D3(5,6-trans-Cholecalciferol) is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.
  • Description
    5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitamin D3. Vitamin D3 is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
  • In Vitro
    Normal human keratinocytes in the cultured human keratinocytes by determining their influence on 3H-thymidine incorporation into DNA.5,6-trans-vitamin D3 only induces significant inhibition at 10(-6) M. The dissociation constants of vitamin D receptor (VDR) for 5,6-trans-vitamin D3 is 560 nM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Vitamin
  • Recptor
    Vitamin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    22350-41-0
  • Formula Weight
    384.64
  • Molecular Formula
    C27H44O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Ethyl Acetate : ≥ 50 mg/mL (129.99 mM)
  • SMILES
    CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1/C[C@@H](O)CCC1=C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. T C Chen, et al. An evaluation of the biologic activity and vitamin D receptor binding affinity of the photoisomers of vitamin D3 and previtamin D3. J Nutr Biochem. 2000 May;11(5):267-72.?
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