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LSN2463359

CAS No. 1401031-52-4

LSN2463359( —— )

Catalog No. M34321 CAS No. 1401031-52-4

LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 50 In Stock
2MG 29 In Stock
5MG 46 In Stock
10MG 73 In Stock
25MG 164 In Stock
50MG 254 In Stock
100MG 375 In Stock
200MG 533 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    LSN2463359
  • Note
    Research use only, not for human use.
  • Brief Description
    LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
  • Description
    LSN2463359 is positive allosteric modulator of metabotropic glutamate 5 (mGlu5). LSN2463359 attenuates aspects of the behavioral response to administration of the competitive NMDA receptor antagonist. LSN2463359 selectively attenuates reversal learning deficits observed in the neurodevelopmental MAM E17 model. LSN2463359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    GluR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1401031-52-4
  • Formula Weight
    265.31
  • Molecular Formula
    C16H15N3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (471.15 mM; Ultrasonic )
  • SMILES
    CC(C)NC(=O)c1ccc(cn1)C#Cc1ccncc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gastambide F, et al. The mGlu? positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat. Neuropharmacology. 2013;64:240-247.?
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