J-104871

CAS No. 191088-19-4

J-104871( —— )

Catalog No. M33992 CAS No. 191088-19-4

J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase (FTase) inhibitor that competitively blocks Ras farnesylation in vivo, inhibits Ras processing in activated H-ras-transformed NIH3T3 cells, and suppresses tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 459 Get Quote
10MG 657 Get Quote
25MG 1026 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    J-104871
  • Note
    Research use only, not for human use.
  • Brief Description
    J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase (FTase) inhibitor that competitively blocks Ras farnesylation in vivo, inhibits Ras processing in activated H-ras-transformed NIH3T3 cells, and suppresses tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.
  • Description
    J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase (FTase) inhibitor that competitively blocks Ras farnesylation in vivo, inhibits Ras processing in activated H-ras-transformed NIH3T3 cells, and suppresses tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    Ras
  • Recptor
    Ras
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    191088-19-4
  • Formula Weight
    708.67
  • Molecular Formula
    C38H32N2O12
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(O)(=O)C1(C(O)=O)O[C@H](C(N([C@@H]([C@H](C/C=C/C2=NC=3C(O2)=CC=CC3)C=4C=C5C(=CC4)OCO5)C)CC6=CC7=C(C=C6)C=CC=C7)=O)[C@H](C(O)=O)O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • 1-(4-methansulfinylp...

    The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.

  • ARS-1323

    ARS1323 is a racemic mixture of ARS-1620/R-atropisomer, ARS-1620 is a potent, specific and covalent KRAS G12C inhibitor.

  • BAY-293 racemate

    BAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM。