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ARS-1323
CAS No. 1698024-73-5
ARS-1323( ARS1323 )
Catalog No. M12590 CAS No. 1698024-73-5
ARS1323 is a racemic mixture of ARS-1620/R-atropisomer, ARS-1620 is a potent, specific and covalent KRAS G12C inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 57 | In Stock |
|
| 2MG | 32 | In Stock |
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| 5MG | 51 | In Stock |
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| 10MG | 86 | In Stock |
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| 25MG | 131 | In Stock |
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| 50MG | 167 | In Stock |
|
| 100MG | 243 | In Stock |
|
| 200MG | 362 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameARS-1323
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NoteResearch use only, not for human use.
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Brief DescriptionARS1323 is a racemic mixture of ARS-1620/R-atropisomer, ARS-1620 is a potent, specific and covalent KRAS G12C inhibitor.
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DescriptionARS1323 is a racemic mixture of ARS-1620/R-atropisomer, ARS-1620 is a potent, specific and covalent KRAS G12C inhibitor with >10-fold improved potency over the initial ARS-853.
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In Vitro——
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In Vivo——
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SynonymsARS1323
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PathwayMAPK/ERK Signaling
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TargetRas
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RecptorRas
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1698024-73-5
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Formula Weight430.84
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Molecular FormulaC21H17ClF2N4O2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 125 mg/mL 290.13 mM
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SMILESC=CC(=O)N1CCN(CC1)C2=NC=NC3=C(C(=C(C=C32)Cl)C4=C(C=CC=C4F)O)F
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Chemical Name1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Janes MR, et al. Cell. 2018 Jan 25;172(3):578-589.e17.
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