Cart
sales@molnova.com
ICI 199,441 hydrochloride
CAS No. 115199-84-3
ICI 199,441 hydrochloride( —— )
Catalog No. M33868 CAS No. 115199-84-3
ICI 199,441 hydrochloride is a potent, selective agonist of κ-opioid receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 53 | In Stock |
|
| 2MG | 28 | In Stock |
|
| 5MG | 44 | In Stock |
|
| 10MG | 69 | In Stock |
|
| 25MG | 141 | In Stock |
|
| 50MG | 221 | In Stock |
|
| 100MG | 325 | In Stock |
|
| 200MG | 456 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameICI 199,441 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionICI 199,441 hydrochloride is a potent, selective agonist of κ-opioid receptor.
-
DescriptionICI 199441 is a potent and selective κ-opioid receptor agonist. ICI 199441 can improve heart resistance to ischemia/reperfusion.
-
In Vitro——
-
In VivoICI 199441 (Wistar rats, 0.1 mg/kg, IV, once) administered 15 min before ischemia produces a potent antiarrhythmic effect.
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetOpioid Receptor
-
RecptorOpioid Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number115199-84-3
-
Formula Weight427.8
-
Molecular FormulaC21H25Cl3N2O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (584.39 mM; Ultrasonic )
-
SMILESCl.CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(Cl)c(Cl)c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Tsibulnikov SY, et al. Prospects of Using of κ-Opioid Receptor Agonists U-50,488 and ICI 199,441 for Improving Heart Resistance to Ischemia/Reperfusion. Bull Exp Biol Med. 2015;159(6):718-721.?
molnova catalog
related products
-
PF-04455242 hydrochl...
PF-04455242 is a potent, selective κ-opioid receptor (KOR) antagonist with Ki of 3 nM/21 nM/22 nM for hKOR/rKOR/mKOR, respectively.
-
DPDPE TFA
DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.
-
Enadoline
Enadoline (CI 977;PD 129290) is a potent, selective κ-opioid receptor (KOR) agonist with Ki of 0.11 nM.
