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BMS986187
CAS No. 684238-37-7
BMS986187( —— )
Catalog No. M24699 CAS No. 684238-37-7
BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 42 | In Stock |
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| 5MG | 68 | In Stock |
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| 10MG | 110 | In Stock |
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| 25MG | 215 | In Stock |
|
| 50MG | 312 | In Stock |
|
| 100MG | 484 | In Stock |
|
| 500MG | 1035 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBMS986187
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NoteResearch use only, not for human use.
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Brief DescriptionBMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.
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DescriptionBMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.
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In VitroBMS-986187?(1 nM-100 uM) produces little or no activity in agonist mode, but in PAM mode (in the presence of an EC20?of leu-enkephalin (in CHO-OPRD1 cells) or endomorphin 1 (in CHO-OPRM1 cells)) produces a response with an EC50?of 48 nM in CHO-OPRD1 cells and 2?μM in CHO-OPRM1 cells.
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetOpioid Receptor
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Recptorδ-opioid receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number684238-37-7
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Formula Weight470.6
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Molecular FormulaC31H34O4
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCC1=CC=CC=C1COC2=CC=C(C=C2)C3C4=C(CC(CC4=O)(C)C)OC5=C3C(=O)CC(C5)(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Livingston K E , Stanczyk M A , Burford N , et al. Pharmacological Evidence for a Putative Conserved Allosteric Site on Opioid Receptors[J]. Molecular Pharmacology, 2017:mol.117.109561.
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