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ER 50891
CAS No. 187400-85-7
ER 50891( —— )
Catalog No. M33848 CAS No. 187400-85-7
ER-50891 is a potent retinoic acid receptor alpha (RARα) antagonist. er-50891 reduces the inhibitory effect of allosteric retinoic acid and restores osteoblast differentiation induced by bone morphogenetic protein 2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 416 | In Stock |
|
| 10MG | 549 | In Stock |
|
| 25MG | 881 | In Stock |
|
| 50MG | 1172 | In Stock |
|
| 100MG | 1562 | In Stock |
|
| 200MG | 2111 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameER 50891
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NoteResearch use only, not for human use.
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Brief DescriptionER-50891 is a potent retinoic acid receptor alpha (RARα) antagonist. er-50891 reduces the inhibitory effect of allosteric retinoic acid and restores osteoblast differentiation induced by bone morphogenetic protein 2.
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DescriptionER-50891 is a potent antagonist of retinoic acid receptor α(RARα). ER-50891 significantly attenuates ATRA's inhibitive effects on BMP 2-induced osteoblastogenesis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetRetinoid Receptor
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RecptorRetinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number187400-85-7
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Formula Weight432.51
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Molecular FormulaC29H24N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC(C)(C)C=1C2=C(C(=CC(=N2)C=3NC(=CC3)C4=CC=C(C(O)=O)C=C4)C5=CC=CC=C5)C=CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Batran RZ, et al. New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways. Bioorg Chem. 2021;111:104817.?
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