Sphingosine-1-phosphate( —— )

Catalog No. M33737 CAS No. 26993-30-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Sphingosine-1-phosphate
Note

Research use only, not for human use.
Brief Description

Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, and GPR12. As an intracellular second messenger, it mobilizes Ca2+ and acts as an extracellular ligand for G-protein coupled receptors.
Description

Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors. Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Endogenous Metabolite | S1P Receptor | LPL Receptor
Research Area

——
Indication

——

CAS Number

26993-30-6
Formula Weight

379.47
Molecular Formula

C18H38NO5P
Purity

>98% (HPLC)
Solubility

In Vitro:?0.5 M NaOH : 3.8 mg/mL (10.01 mM; Ultrasonic (<60°C))DMSO : < 1 mg/mL (insoluble or slightly soluble)
SMILES

[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)(COP(=O)(O)O)N
Chemical Name

——

1. Teresa Sanchez, et al. Structural and Functional Characteristics of S1P Receptors. J Cell Biochem. 2004 Aug 1;92(5):913-22.?

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