CD3254
CAS No. 196961-43-0
CD3254( —— )
Catalog No. M33310 CAS No. 196961-43-0
CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCD3254
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NoteResearch use only, not for human use.
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Brief DescriptionCD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.
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DescriptionCD3254 a potent and selective retinoid-X-receptor (RXR) agonist.
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In VitroCell Viability AssayCell Line:zebrafish (Danio rerio) embryosConcentration:10, 20, 50, 100 μg/L Incubation Time:Result:The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetRetinoid Receptor
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RecptorRetinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number196961-43-0
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Formula Weight364.48
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Molecular FormulaC24H28O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (342.95 mM; Ultrasonic )
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SMILESCc1cc2c(cc1-c1cc(\C=C/C(O)=O)ccc1O)C(C)(C)CCC2(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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WYC209
WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).
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ER 50891
ER-50891 is a potent retinoic acid receptor alpha (RARα) antagonist. er-50891 reduces the inhibitory effect of allosteric retinoic acid and restores osteoblast differentiation induced by bone morphogenetic protein 2.
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BMS493
BMS493 is an inverse agonist of the pan-retinoic acid receptor (RAR) that inhibits retinoic acid-induced differentiation, enhances the interaction of nuclear co-inhibitors with RARs, attenuates RA signaling, potentiates TPP-induced toxicity, and inhibits the increase in phospholipase A2 activity.
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