Cart
sales@molnova.com
Home - Products - Chromatin/Epigenetic - Epigenetic Reader Domain - SMARCA-BD ligand 1 for Protac dihydrochloride

SMARCA-BD ligand 1 for Protac dihydrochloride

CAS No. 2369053-68-7

SMARCA-BD ligand 1 for Protac dihydrochloride( —— )

Catalog No. M33234 CAS No. 2369053-68-7

SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunit SMARCA2 and is used for degrading SMARCA2 based on PROTAC.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 84 In Stock
10MG 136 In Stock
25MG 226 In Stock
50MG 317 In Stock
100MG 434 In Stock
200MG 602 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SMARCA-BD ligand 1 for Protac dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunit SMARCA2 and is used for degrading SMARCA2 based on PROTAC.
  • Description
    SMARCA-BD ligand 1 for Protac dihydrochloride is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    Epigenetic Reader Domain
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2369053-68-7
  • Formula Weight
    344.24
  • Molecular Formula
    C14H19Cl2N5O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 2.7 mg/mL (7.84 mM; Ultrasonic (<60°C)
  • SMILES
    Cl.Cl.Nc1nnc(cc1N1CCNCC1)-c1ccccc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Curcumin

    Curcumin is a natural phenolic compound with impressive antioxidant properties. Curcumin is recently proved to exert its chemopreventive effects partly through the activation of nuclear factor (erythroid-2 related) factor 2 (Nrf2).

  • FHD-286

    FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.

  • CPI-203

    CPI-203 is a potent BET bromodomain inhibitor with IC50 of 37 nM for BRD4.

Sign In Join Free