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Compound 48/80 trihydrochloride
CAS No. 848035-21-2
Compound 48/80 trihydrochloride( —— )
Catalog No. M33209 CAS No. 848035-21-2
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde produced via a condensation reaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 94 | In Stock |
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| 2MG | 53 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCompound 48/80 trihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionCompound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde produced via a condensation reaction.
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DescriptionCompound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets .
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In Vitro——
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In VivoAnimal Model:7-week-old Wistar male rats (fasted for 24 hours) Dosage:0.75 mg/kg Administration:Intraperitoneal injection; Killed after 0.5, 3 or 6 h Result:Serum histamine and serotonin concentrations significantly higher than those in untreated control rats at 0.5 h after treatment. The increased serum histamine and serotonin concentrations in rats decreased time-dependently thereafter.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhospholipase
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RecptorPhospholipase
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Research Area——
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Indication——
Chemical Information
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CAS Number848035-21-2
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Formula Weight629.1
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Molecular FormulaC32H48Cl3N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 25 mg/mL (39.74 mM; Ultrasonic) DMSO : 10 mg/mL (15.90 mM; Ultrasonic (<60°C)
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SMILESCl.Cl.Cl.CNCCc1ccc(OC)c(Cc2cc(CCNC)cc(Cc3cc(CCNC)ccc3OC)c2OC)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bronner C, et al. Compound 48/80 is a potent inhibitor of phospholipase C and a dual modulator of phospholipase A2 from human platelet. Biochim Biophys Acta. 1987 Aug 15;920(3):301-5.?
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