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AZ-1355
CAS No. 75451-07-9
AZ-1355( —— )
Catalog No. M33202 CAS No. 75451-07-9
AZ-1355 is a novel dibenzoxepine derivative with lipid-lowering properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 159 | In Stock |
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| 5MG | 174 | In Stock |
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| 10MG | 236 | In Stock |
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| 25MG | 356 | In Stock |
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| 50MG | 476 | In Stock |
|
| 100MG | 620 | In Stock |
|
| 200MG | 846 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAZ-1355
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NoteResearch use only, not for human use.
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Brief DescriptionAZ-1355 is a novel dibenzoxepine derivative with lipid-lowering properties.
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DescriptionAZ-1355 is an effctive lipid-lowering compound, which also inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2 ratio in vitro.
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In Vitro——
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In VivoAZ-1355 (50 mg/kg) significantly reduces serum TG and the 100 mg/kg dose results in serum TC and TG reduction in rat. AZ-1355 (100 mg/kg) reduces total liver TC in rats fed CE-2, and the 50 mg/kg dose reduces hepatic TC in rats fed the high fat diet on both bases, and it also reduces the total hepatic TG of the CE-2 fed rats. AZ-1355 (150 mg/kg) reproducibly lowers serum total cholesterol (TC) in the Triton hyperlipidemic mice.
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Synonyms——
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PathwayGPCR/G Protein
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TargetProstaglandin Receptor
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RecptorProstaglandin Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number75451-07-9
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Formula Weight299.32
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Molecular FormulaC17H17NO4
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Purity>98% (HPLC)
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Solubility——
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SMILESO(C)C1=C2C(CNC=3C(O2)=CC=C(C(OCC)=O)C3)=CC=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wada S, et al. The lipid-lowering profile in rodents. AZ-1355, a new dibenzoxazepine derivative. Atherosclerosis. 1981 Nov-Dec;40(3-4):263-71.?
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