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Omidenepag
CAS No. 1187451-41-7
Omidenepag( —— )
Catalog No. M33447 CAS No. 1187451-41-7
Omidenepag (UR-7276) is a selective and potent prostaglandin E2 receptor 2 (EP2) agonist and a novel topical ocular hypotensive agent.Omidenepag is used in the study of glaucoma and hypertension.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 105 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameOmidenepag
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NoteResearch use only, not for human use.
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Brief DescriptionOmidenepag (UR-7276) is a selective and potent prostaglandin E2 receptor 2 (EP2) agonist and a novel topical ocular hypotensive agent.Omidenepag is used in the study of glaucoma and hypertension.
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DescriptionOmidenepag (UR-7276), a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetProstaglandin Receptor
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RecptorProstaglandin Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1187451-41-7
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Formula Weight478.52
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Molecular FormulaC23H22N6O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (522.44 mM; Ultrasonic )
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SMILESOC(=O)CNc1cccc(CN(Cc2ccc(cc2)-n2cccn2)S(=O)(=O)c2cccnc2)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Iwamura R, et al. Identification?of a?Selective,?Non-Prostanoid?EP2?Receptor?Agonist?for the?Treatment?of?Glaucoma:?Omidenepag?and its?Prodrug?Omidenepag?Isopropyl. J Med Chem.?2018 Aug 9;61(15):6869-6891.?
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