Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Prostaglandin Receptor - Omidenepag

Omidenepag

CAS No. 1187451-41-7

Omidenepag( —— )

Catalog No. M33447 CAS No. 1187451-41-7

Omidenepag (UR-7276) is a selective and potent prostaglandin E2 receptor 2 (EP2) agonist and a novel topical ocular hypotensive agent.Omidenepag is used in the study of glaucoma and hypertension.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 93 In Stock
5MG 93 In Stock
10MG 148 In Stock
25MG 302 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Omidenepag
  • Note
    Research use only, not for human use.
  • Brief Description
    Omidenepag (UR-7276) is a selective and potent prostaglandin E2 receptor 2 (EP2) agonist and a novel topical ocular hypotensive agent.Omidenepag is used in the study of glaucoma and hypertension.
  • Description
    Omidenepag (UR-7276), a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Prostaglandin Receptor
  • Recptor
    Prostaglandin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1187451-41-7
  • Formula Weight
    478.52
  • Molecular Formula
    C23H22N6O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (522.44 mM; Ultrasonic )
  • SMILES
    OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-n2cccn2)S(=O)(=O)c2cccnc2)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Iwamura R, et al. Identification?of a?Selective,?Non-Prostanoid?EP2?Receptor?Agonist?for the?Treatment?of?Glaucoma:?Omidenepag?and its?Prodrug?Omidenepag?Isopropyl. J Med Chem.?2018 Aug 9;61(15):6869-6891.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Grapiprant

    A novel EP4 antagonist; an analgesic and anti-inflammatory drug in the piprant class that was approved for Veterinary Medicine for the control of pain and inflammation.

  • Tafluprost

    Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α.Tafluprost showed significant IOP-lowering effects without any safety concerns in patients with various types of glaucoma and OH in daily clinical practice and tafluprost is highly effective in any therapeutic pattern.

  • 7-demethylsuberosin

    7-demethylsuberosin?is a coumarin compound isolated from Angelica gigas Nakaiand has anti-inflammatory activityand exhibited ?inhibitory effects on PGE2 production with the IC50 values of 9.42 μM.

Sign In Join Free