AMP-PCP disodium( —— )

Catalog No. M33199 CAS No. 7414-56-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

AMP-PCP disodium
Note

Research use only, not for human use.
Brief Description

AMP-PCP disodium, an ATP analogue, binds to the N-terminal domain of Hsp90 with a Kd value of 3.8 μM, facilitating the formation of an active Hsp90 homodimer.
Description

AMP-PCP disodium is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP disodium binding favors the formation of the active homodimer of Hsp90.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

HSP
Recptor

HSP
Research Area

——
Indication

——

CAS Number

7414-56-4
Formula Weight

549.17
Molecular Formula

C11H16N5Na2O12P3
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : 100 mg/mL (182.09 mM; Ultrasonic)
SMILES

O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(CP([O-])([O-])=O)(O)=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.[Na+].[Na+]
Chemical Name

——

1. Zhang H, et al. A dynamic view of ATP-coupled functioning cycle of Hsp90 N-terminal domain. Sci Rep. 2015 Apr 13;5:9542.?

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