HS-131( HS131 )

Catalog No. M17005 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

HS-131
Note

Research use only, not for human use.
Brief Description

HS-131 is an imaging probe of Hsp90 activity by linking it to a near-infrared (nIR) dye.
Description

HS-131 is an imaging probe of Hsp90 activity by linking it to a near-infrared (nIR) dye, HS131 uptake into cells correlated with cell membrane expression of Hsp90 and was used to image molecular subtypes of murine and human breast cancers in vitro and in murine models.
In Vitro

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In Vivo

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Synonyms

HS131
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

HSP
Recptor

HSP
Research Area

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Indication

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CAS Number

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Formula Weight

1318.697
Molecular Formula

C71H95N7O13S2
Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

4-(2-((1E,3Z)-3-(4-(21-((2-carbamoyl-5-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)-6,9,12,15,18-pentaoxa-2-azahenicosyl)phenyl)-5-((E)-3,3-dimethyl-1-(4-sulfobutyl)indolin-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-3H-indol-1-

1. Osada T, et al. Clin Cancer Res. 2017 Dec 15;23(24):7531-7542.

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