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MCL-1/BCL-2-IN-2
CAS No. 2163793-44-8
MCL-1/BCL-2-IN-2( —— )
Catalog No. M33012 CAS No. 2163793-44-8
MCL-1/BCL-2-IN-2 is a potent and selective dual inhibitor of Bcl-2 and Mcl-1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 73 | In Stock |
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| 25MG | 135 | In Stock |
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| 50MG | 212 | In Stock |
|
| 100MG | 346 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMCL-1/BCL-2-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionMCL-1/BCL-2-IN-2 is a potent and selective dual inhibitor of Bcl-2 and Mcl-1.
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DescriptionMCL-1/BCL-2-IN-2 (Compound 6) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBCL
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Research Area——
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Indication——
Chemical Information
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CAS Number2163793-44-8
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Formula Weight427.31
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Molecular FormulaC20H15BrN2O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 5 mg/mL (11.70 mM; Ultrasonic (<60°C)
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SMILESNCCN1C(=O)c2cccc3c(Sc4ccc(Br)cc4)ccc(C1=O)c23
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.?
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