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TCPOBOP
CAS No. 76150-91-9
TCPOBOP( —— )
Catalog No. M24766 CAS No. 76150-91-9
TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 43 | In Stock |
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| 10MG | 65 | In Stock |
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| 25MG | 120 | In Stock |
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| 50MG | 193 | In Stock |
|
| 100MG | 305 | In Stock |
|
| 200MG | 458 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTCPOBOP
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NoteResearch use only, not for human use.
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Brief DescriptionTCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.
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DescriptionTCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly. TCPOBOP decreases Fas-induced murine liver injury by altering Bcl-2 proteins.
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In Vitro——
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In VivoTCPOBOP (oral; 3 mg/kg; 1-5 days) remarkable increases Liver weight to body weight in LW/BW ratio at 48 hours. Animal Model:METfl/fl: Tam-Cre+/+ mice with a targeted deletion for exon 16 with MET KO Dosage:3 mg/kg.Administration:Oral; 1, 2, 5 days Result:Increased Liver weight to body weight.
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Synonyms——
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBcl-2
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Research Area——
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Indication——
Chemical Information
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CAS Number76150-91-9
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Formula Weight402.06
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Molecular FormulaC16H8Cl4N2O2
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Purity>98% (HPLC)
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SolubilityDMSO:25 mg/mL?(62.18 mM;?ultrasonic and warming and heat to 50°C)
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SMILESClC1=CN=C(OC2=CC=C(OC3=NC=C(Cl)C=C3Cl)C=C2)C(Cl)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Bcl-xL antagonist 2
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic leukemia and non-Hodgkin’s lymphoma.
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Allethrin
Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.
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Aromadendrin
Aromadendrin is a natural product.?It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression,?possesses anti-inflammatory, antioxidant, and anti-diabetic properties, it exhibits anti-inflammatory activityAromadendrin, a flavonol, has been reported to possess a variety of pharmacological activities such as anti-inflammatory, antioxidant, and anti-diabetic properties.?
