GSK-3 inhibitor 1
CAS No. 603272-51-1
GSK-3 inhibitor 1( —— )
Catalog No. M32946 CAS No. 603272-51-1
GSK-3 inhibitor 1 is a GSK-3 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 240 | In Stock |
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| 5MG | 217 | In Stock |
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| 10MG | 353 | In Stock |
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| 25MG | 676 | In Stock |
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| 50MG | 986 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK-3 inhibitor 1
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NoteResearch use only, not for human use.
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Brief DescriptionGSK-3 inhibitor 1 is a GSK-3 inhibitor.
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DescriptionGSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.g. induces stem/progenitor cell proliferation while maintaining the ability to differentiate into tissue cells in the progeny).
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In VitroGSK-3 inhibitor 1 can be used to induce, promote or enhance the growth, proliferation or regeneration of inner ear tissues such as inner ear supporting cells or inner ear hair cells.
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetGSK-3
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RecptorGSK-3
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Research Area——
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Indication——
Chemical Information
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CAS Number603272-51-1
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Formula Weight437.85
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Molecular FormulaC22H17ClFN5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 12.5 mg/mL (28.55 mM; Ultrasonic (<60°C)
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SMILESCl.Fc1cc2CNCCn3cc(C4=C(C(=O)NC4=O)c4cnc5ccccn45)c(c1)c23
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CHIR-99021
A potent, specific GSK-3 inhibitor with IC50 of 5 nM and 10 nM for GSK3β and GSK3α, respectively.
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Dihydroergotoxine me...
It is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.
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9-ING-41
9-ING-41 is a glycogen synthase kinase-3 inhibitor.9-ING-41 (2, 4 μM; 48 hours) decreases neuroblastoma cell viability induces apoptosis[2]. 9-ING-41 (0.1-1 μM) inhibits GSK-3 leading to a decreased expression of the NF-κB target XIAP and significant apoptosis in neuroblastoma cells as shown by PARP cleavage, an apoptosis marker[1]. 9-ING-41 (0.5, 1.0, 1.5, 2.0 μM) inhibits the proliferation rate of all TCL and MCL lines with concentrations as low as 1.0 mM.
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