Cart
sales@molnova.com
Bikinin
CAS No. 188011-69-0
Bikinin( Abrasin )
Catalog No. M12915 CAS No. 188011-69-0
Bikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 35 | In Stock |
|
| 25MG | 63 | In Stock |
|
| 50MG | 110 | In Stock |
|
| 100MG | 177 | In Stock |
|
| 200MG | 264 | In Stock |
|
| 500MG | 447 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBikinin
-
NoteResearch use only, not for human use.
-
Brief DescriptionBikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor.
-
DescriptionBikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor, binds and inhibits Arabidopsis thaliana GSK3-like kinases; interferes directly with BIN2 kinase activity, also strongly inhibited the activity of the group I Arabidopsis GSK3 subfamilies, but not the ASKβ, ASKδ, and other Arabidopsis Ser/Thr kinases (AtMPK4, AtMPK6, and AtAURORA1); inhibits the SnRK2.3 kinase activity and its T180 phosphorylation in vivo.
-
In Vitro——
-
In Vivo——
-
SynonymsAbrasin
-
PathwayPI3K/Akt/mTOR signaling
-
TargetGSK-3
-
RecptorGSK-3|Shaggy-likekinase
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number188011-69-0
-
Formula Weight273.0834
-
Molecular FormulaC9H9BrN2O3
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 42 mg/mL
-
SMILESBrC1=CN=C(NC(CCC(O)=O)=O)C=C1
-
Chemical NameButanoic acid, 4-[(5-bromo-2-pyridinyl)amino]-4-oxo-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. De Rybel B, et al. Chem Biol. 2009 Jun 26;16(6):594-604.
2. Cai Z, et al. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9651-6.
3. Rozhon W, et al. BMC Plant Biol. 2014 Jun 19;14:172.
molnova catalog
related products
-
TDZD-8
A potent, selective, non-ATP competitive GSK-3β inhibitor with IC50 of 2 uM; displays no activity against PKA, CK-2, PKC, and CDK1 (IC50>100 uM).
-
GSK3-IN-3
GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.
-
BRD1172
BRD1172 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 3 nM/10 nM for GSK3α/GSK3β, respectively.
