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Bikinin
CAS No. 188011-69-0
Bikinin( Abrasin )
Catalog No. M12915 CAS No. 188011-69-0
Bikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 37 | In Stock |
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| 25MG | 67 | In Stock |
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| 50MG | 113 | In Stock |
|
| 100MG | 183 | In Stock |
|
| 200MG | 272 | In Stock |
|
| 500MG | 462 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBikinin
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NoteResearch use only, not for human use.
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Brief DescriptionBikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor.
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DescriptionBikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor, binds and inhibits Arabidopsis thaliana GSK3-like kinases; interferes directly with BIN2 kinase activity, also strongly inhibited the activity of the group I Arabidopsis GSK3 subfamilies, but not the ASKβ, ASKδ, and other Arabidopsis Ser/Thr kinases (AtMPK4, AtMPK6, and AtAURORA1); inhibits the SnRK2.3 kinase activity and its T180 phosphorylation in vivo.
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In Vitro——
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In Vivo——
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SynonymsAbrasin
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PathwayPI3K/Akt/mTOR signaling
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TargetGSK-3
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RecptorGSK-3|Shaggy-likekinase
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number188011-69-0
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Formula Weight273.0834
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Molecular FormulaC9H9BrN2O3
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 42 mg/mL
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SMILESBrC1=CN=C(NC(CCC(O)=O)=O)C=C1
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Chemical NameButanoic acid, 4-[(5-bromo-2-pyridinyl)amino]-4-oxo-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. De Rybel B, et al. Chem Biol. 2009 Jun 26;16(6):594-604.
2. Cai Z, et al. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9651-6.
3. Rozhon W, et al. BMC Plant Biol. 2014 Jun 19;14:172.
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