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Home - Products - Metabolic Enzyme/Protease - Phosphatase - 7-BIA

7-BIA

CAS No. 1313403-49-4

7-BIA( —— )

Catalog No. M32759 CAS No. 1313403-49-4

7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties, and is utilized in neuropathic pain research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    7-BIA
  • Note
    Research use only, not for human use.
  • Brief Description
    7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties, and is utilized in neuropathic pain research.
  • Description
    7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with an IC50 of ~1-3 μM.
  • In Vitro
    ——
  • In Vivo
    Animal Model:WT mice (available cocaine 50 times, 1 mg/kg infusions on FR1 schedule during ≥20 prior sessions) Dosage:10 mg/kg, 20 mg/kg Administration:Given i.p.; only once Result:Reduced cocaine self-administration in highly experienced WT mice.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Phosphatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1313403-49-4
  • Formula Weight
    294.3
  • Molecular Formula
    C15H18O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (424.74 mM; Ultrasonic ) Ethanol : 50 mg/mL (169.89 mM; Ultrasonic)
  • SMILES
    CCCCOc1cc2C(=O)OC(O)Cc2c(C=O)c1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Uhl GR, et al. Cocaine reward is reduced by decreased expression of receptor-type protein tyrosinephosphatase D (PTPRD) and by a novel PTPRD antagonist. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11597-11602.?
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