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Home - Products - Metabolic Enzyme/Protease - Phosphatase - 7-BIA

7-BIA

CAS No. 1313403-49-4

7-BIA( —— )

Catalog No. M32759 CAS No. 1313403-49-4

7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties, and is utilized in neuropathic pain research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 377 In Stock
5MG 353 In Stock
10MG 613 In Stock
25MG 1131 In Stock
50MG 1748 In Stock
100MG 2771 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    7-BIA
  • Note
    Research use only, not for human use.
  • Brief Description
    7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties, and is utilized in neuropathic pain research.
  • Description
    7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with an IC50 of ~1-3 μM.
  • In Vitro
    ——
  • In Vivo
    Animal Model:WT mice (available cocaine 50 times, 1 mg/kg infusions on FR1 schedule during ≥20 prior sessions) Dosage:10 mg/kg, 20 mg/kg Administration:Given i.p.; only once Result:Reduced cocaine self-administration in highly experienced WT mice.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Phosphatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1313403-49-4
  • Formula Weight
    294.3
  • Molecular Formula
    C15H18O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (424.74 mM; Ultrasonic ) Ethanol : 50 mg/mL (169.89 mM; Ultrasonic)
  • SMILES
    CCCCOc1cc2C(=O)OC(O)Cc2c(C=O)c1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Uhl GR, et al. Cocaine reward is reduced by decreased expression of receptor-type protein tyrosinephosphatase D (PTPRD) and by a novel PTPRD antagonist. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11597-11602.?
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