TAPI 0
CAS No. 163958-73-4
TAPI 0( —— )
Catalog No. M30787 CAS No. 163958-73-4
ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameTAPI 0
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NoteResearch use only, not for human use.
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Brief DescriptionADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.
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DescriptionADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.
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In VitroTAPI-0 inhibits peptide deformylase (PDF) with an IC50 of 18 nM.TAPI-0 suppresses chlamydial growth by targeting the bacterial PDF.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number163958-73-4
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Formula Weight456.54
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Molecular FormulaC24H32N4O5
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Purity>98% (HPLC)
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SolubilityDMSO:10 mg/mL
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SMILESONC(C[C@@H](CC(C)C)C(N[C@@H](CC1=CC(C=CC=C2)=C2C=C1)C(N[C@@H](C)C(N)=O)=O)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Epitheaflagallin 3-O...
Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts.
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CTTHWGFTLC, CYCLIC
This cyclic CTT Gelatinase Inhibitor peptide is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9. It is also called type IV collagenase or gelatinase. Gelatinases are potential targets of therapeutic intervention in cancer, and inhibitors of these enzymes can prevent tumor progression.
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MMP-9-IN-1
MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).
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