Cyclo(RGDyK)( —— )

Catalog No. M30392 CAS No. 217099-14-4

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Cyclo(RGDyK)
Note

Research use only, not for human use.
Brief Description

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
Description

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.(In Vitro):Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM).
In Vitro

Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5(IC50=4000 nM) and αIIbβ3 (IC50=3000 nM).
In Vivo

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Synonyms

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Pathway

Cell Cycle/DNA Damage
Target

Integrin
Recptor

IC50: 20 nM (αVβ3 Integrin), 3000 nM (αIIbβ3 Integrin), 4000 nM (αVβ5 Integrin)
Research Area

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Indication

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Chemical Information

CAS Number

217099-14-4
Formula Weight

619.67
Molecular Formula

C27H41N9O8
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 5 mg/mL (8.07 mM)
SMILES

——
Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.

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