GSK-3008348( GSK3008348 )

Catalog No. M12439 CAS No. 1629249-33-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

GSK-3008348
Note

Research use only, not for human use.
Brief Description

GSK-3008348 is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF).
Description

GSK-3008348 is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF).Cystic Fibrosis Phase 1 Clinical.
In Vitro

——
In Vivo

——
Synonyms

GSK3008348
Pathway

Cell Cycle/DNA Damage
Target

Integrin
Recptor

Integrin
Research Area

Other Indications
Indication

Fibrosis

CAS Number

1629249-33-7
Formula Weight

487.636
Molecular Formula

C29H37N5O2
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

O=C(O)C[C@@H](C1=CC=CC(N2N=C(C)C=C2C)=C1)CN3C[C@@H](CCC4=NC5=C(CCCN5)C=C4)CC3
Chemical Name

(3S)-3-[3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl]-4-{(3S)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]-1-pyrrolidinyl}butanoic acid