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Valategrast hydrochloride
CAS No. 828271-96-1
Valategrast hydrochloride( R-411 | RO-0272441 | RO-27-2441 | R411 | RO 0272441 | RO 27 2441 )
Catalog No. M16076 CAS No. 828271-96-1
Valategrast hydrochloride is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 382 | Get Quote |
|
| 50MG | 1962 | Get Quote |
|
| 100MG | 2520 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameValategrast hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionValategrast hydrochloride is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.
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DescriptionValategrast hydrochloride is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.Asthma Discontinued.
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In VitroValategrast (hydrochloride) contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS).
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In Vivo——
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SynonymsR-411 | RO-0272441 | RO-27-2441 | R411 | RO 0272441 | RO 27 2441
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorIntegrin
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Research AreaInflammation/Immunology
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IndicationAsthma
Chemical Information
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CAS Number828271-96-1
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Formula Weight641.411
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Molecular FormulaC30H33Cl4N3O4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(OCCN(CC)CC)[C@H](CC1=CC=C(NC(C2=C(Cl)C=CC=C2Cl)=O)C=C1)NC(C3=C(C)C=CC=C3Cl)=O.[H]Cl
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Chemical Name2-(diethylamino)ethyl (2S)-2-[(2-chloro-6-methylbenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoate hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sidduri A, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2479-82.
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