Cart
sales@molnova.com
ILK-IN-3
CAS No. 6975-75-3
ILK-IN-3( —— )
Catalog No. M22072 CAS No. 6975-75-3
ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 164 | In Stock |
|
| 10MG | 262 | In Stock |
|
| 25MG | 471 | In Stock |
|
| 50MG | 683 | In Stock |
|
| 100MG | 954 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameILK-IN-3
-
NoteResearch use only, not for human use.
-
Brief DescriptionILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.
-
DescriptionILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.(In Vitro):ILK-IN-3 (compound 4, 10 μM) inhibits DYRK1, GSK3α/β, CDK5/p25 kinase activity to 17%, 51%, 47%, 95%, respectively.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetIntegrin
-
RecptorIntegrin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number6975-75-3
-
Formula Weight232.24
-
Molecular FormulaC10H12N6O?
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 83.33 mg/mL (358.81 mM)
-
SMILESCOC1=CC=C(C=C1)N=NC2=C(NN=C2N)N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Cilengitide trifluor...
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
-
MK-0429
MK-0429 is a potent, selective, orally-active nonpeptide αvβ3 integrin inhibitor with IC50 of 0.08 nM in SPAV3 assay.
-
Fibronectin CS1 Pept...
he connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models. The use of Fibronectin CS1 Peptide might offer a promising therapeutic approach for combating and preventing cancer metastasis.
