ACTH (4-10), human
CAS No. 4037-01-8
ACTH (4-10), human( Adrenocorticotropic Hormone (ACTH) (4-10), human )
Catalog No. M29938 CAS No. 4037-01-8
Adrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist. Adrenocorticotropic Hormones (ACTH). ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Another name for ACTH is corticotropin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 42 | Get Quote |
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| 5MG | 68 | Get Quote |
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| 10MG | 105 | Get Quote |
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| 25MG | 215 | Get Quote |
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| 50MG | 279 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameACTH (4-10), human
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NoteResearch use only, not for human use.
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Brief DescriptionAdrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist. Adrenocorticotropic Hormones (ACTH). ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Another name for ACTH is corticotropin.
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DescriptionAdrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist. Adrenocorticotropic Hormones (ACTH). ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Another name for ACTH is corticotropin.(In Vitro):Adrenocorticotropic Hormone (ACTH) (4-10), human (ACTH (4-10)) is the core sequence of all melanocortins and binds selectively to MC4-R. In humans, ACTH (4-10) enters the cerebral fluid compartment after intranasal application and leads to a decrease in total body fat after 6 weeks of continuous treatment.
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In Vitro——
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In Vivo——
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SynonymsAdrenocorticotropic Hormone (ACTH) (4-10), human
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PathwayGPCR/G Protein
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TargetMelanocortin Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number4037-01-8
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Formula Weight962.09
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Molecular FormulaC44H59N13O10S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (25.99 mM)
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SMILES——
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Chemical NameSequence:Met-Glu-His-Phe-Arg-Trp-Gly
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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JNJ-10229570
JNJ-10229570 (JNJ10229570) is a novel potent, selective melanocortin receptor MC1R and MC5R antagonist with binding IC50 of 270 nM and 200 nM, respectively.
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Dersimelagon
Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values ??of 8.16, 3.91, 1.14, and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m), and rat (r) MC1R, respectively.
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γ1-MSH
Endogenous melanocortin MC3 receptor agonist (pKi = 7.46) that displays ~ 40-fold selectivity over MC4. Increases the release of extracellular dopamine, which induces grooming and vertical activity (rearing) in rats. Exhibits hypertensive, tachycardic and short-term analgesic activity in vivo.
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