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AP1189 acetate
CAS No. 959850-74-9
AP1189 acetate( —— )
Catalog No. M28790 CAS No. 959850-74-9
AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 104 | In Stock |
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| 5MG | 79 | In Stock |
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| 10MG | 129 | In Stock |
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| 25MG | 235 | In Stock |
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| 50MG | 342 | In Stock |
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| 100MG | 486 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAP1189 acetate
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NoteResearch use only, not for human use.
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Brief DescriptionAP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
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DescriptionAP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.(In Vitro):Added to macrophage cultures, AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes.(In Vivo):Oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ～3-fold.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetMelanocortin Receptor
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Recptorcalmodulin
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Research Area——
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Indication——
Chemical Information
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CAS Number959850-74-9
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Formula Weight358.35
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Molecular FormulaC16H18N6O4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=[N+](C1=CC=CC=C1N2C(/C=C/C=N/NC(N)=N)=CC=C2)[O-].CC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Noriko Koizumi, et al. Combined agent for cell therapy of corneal endothelial cell. US10959997B2
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