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PG 106
CAS No. 944111-22-2
PG 106( —— )
Catalog No. M30584 CAS No. 944111-22-2
Selective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NamePG 106
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NoteResearch use only, not for human use.
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Brief DescriptionSelective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.
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DescriptionSelective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetMelanocortin Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number944111-22-2
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Formula Weight1008.19
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Molecular FormulaC51H69N13O9
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Purity>98% (HPLC)
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Solubility25% ethanol / water:1 mg/mL
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SMILES[H]N([C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC2=CC3=CC=CC=C3C=C2)NC(=O)CCNC1=O)C(N)=O)C(=O)C(CCCC)NC(C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Grieco et al (2007) Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides. 28 1191 PMID:
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