Cart
sales@molnova.com
Bremelanotide acetate
CAS No. 1607799-13-2
Bremelanotide acetate( PT-141 acetate )
Catalog No. M12310 CAS No. 1607799-13-2
Bremelanotide acetate is an analogue of the naturally occurring peptide alpha-MSH; melanocortin receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 62 | In Stock |
|
| 10MG | 44 | In Stock |
|
| 25MG | 79 | In Stock |
|
| 50MG | 129 | In Stock |
|
| 100MG | 193 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBremelanotide acetate
-
NoteResearch use only, not for human use.
-
Brief DescriptionBremelanotide acetate is an analogue of the naturally occurring peptide alpha-MSH; melanocortin receptor agonist.
-
DescriptionBremelanotide acetate is an analogue of the naturally occurring peptide alpha-MSH; melanocortin receptor agonist.Sexual Dysfunction Phase 3 Clinical(In Vivo):Bremelanotide Acetate (50-200 μg/kg; s.c.; once) significantly increases proceptive solicitations in females primed with Estradiol benzoate+Progesterone or Estradiol benzoate alone in bilevel chambers.
-
In Vitro——
-
In VivoBremelanotide Acetate (50-200 μg/kg; s.c.; once) significantly increases proceptive solicitations in females primed with Estradiol benzoate+Progesterone or Estradiol benzoate alone in bilevel chambers. Animal Model:Ovariectomized Long–Evans rats Dosage:50, 100, 200 μg/kg Administration:s.c.; once Result:Significantly increased proceptive solicitations in females primed with Estradiol benzoate+Progesterone or Estradiol benzoate alone in bilevel chambers.
-
SynonymsPT-141 acetate
-
PathwayGPCR/G Protein
-
TargetMelanocortin Receptor
-
RecptorMelanocortin Receptor
-
Research AreaEndocrinology
-
IndicationSexual Dysfunction
Chemical Information
-
CAS Number1607799-13-2
-
Formula Weight1085.215
-
Molecular FormulaC52H72N14O12
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 36 mg/mL
-
SMILESCCCCC(C(=O)NC1CC(=O)NCCCCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC2=CN=CN2)CC3=CC=CC=C3)CCCN=C(N)N)CC4=CNC5=CC=CC=C54)C(=O)O)NC(=O)C.CC(=O)O
-
Chemical Name(3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((S)-2-acetamidohexanamido)-9-benzyl-6-(3-guanidinopropyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxylic acid with acetic acid (1:1)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Pfaus J, et al. J Sex Med. 2007 Nov;4 Suppl 4:269-79.
2. White WB, et al. J Hypertens. 2017 Apr;35(4):761-768.
molnova catalog
related products
-
RO 27-3225
RO 27-3225 (RO27-3225, RO 273225) is a potent, selective melanocortin melanocortin receptor MC4R agonist with EC50 of 1 nM.
-
THIQ
THIQ is a selective melanocortin-4 receptor (MC4R)?agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).?
-
JKC 363
Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, attenuates food intake and reduces formalin-induced pain in vivo.
