Cart
sales@molnova.com
N-Caffeoyltryptophan
CAS No. 109163-69-1
N-Caffeoyltryptophan( trans-Caffeoyl-L-tryptophan )
Catalog No. M29476 CAS No. 109163-69-1
N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 246 | In Stock |
|
| 2MG | 141 | In Stock |
|
| 5MG | 227 | In Stock |
|
| 10MG | 337 | In Stock |
|
| 25MG | 559 | In Stock |
|
| 50MG | 779 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameN-Caffeoyltryptophan
-
NoteResearch use only, not for human use.
-
Brief DescriptionN-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
-
DescriptionN-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).(In Vitro):In cellular levels,N-Caffeoyltryptophan was able to increase the acetylation of total lysine, cortactin and histone H3 in neuronal NG108-15 cells. In the same cells, the amide also increased the acetylation of lysine (K382) in p53, but not (K305).
-
In Vitro——
-
In Vivo——
-
Synonymstrans-Caffeoyl-L-tryptophan
-
PathwayChromatin/Epigenetic
-
TargetSirtuin
-
RecptorSirtuin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number109163-69-1
-
Formula Weight366.373
-
Molecular FormulaC20H18N2O5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)\C=C\c1ccc(O)c(O)c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
Z26395438
Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM.
-
SirReal2 (b)
SirReal2 (MZ25) is a novel potent, selective Sirt2 inhibitor with IC50 of 0.435 uM.
-
UBCS039
UBCS039 (UBCS-039) is the first synthetic activator of the NAD+-dependent protein lysine deacetylase SIRT6 with EC50 of 38 uM.
