NPX800

CAS No. 1693734-80-3

NPX800( CCT361814 )

Catalog No. M28911 CAS No. 1693734-80-3

NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 300 In Stock
5MG 239 In Stock
10MG 375 In Stock
25MG 626 In Stock
50MG 873 In Stock
100MG 1190 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    NPX800
  • Note
    Research use only, not for human use.
  • Brief Description
    NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.
  • Description
    NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.(In Vitro):NPX800 inhibits cell viability of U20S with IC50 of 56 nM.
  • In Vitro
    NXP800 (example 169) inhibits U20S cells viability (IC50=0.056 μM).
  • In Vivo
    ——
  • Synonyms
    CCT361814
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    Eg5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1693734-80-3
  • Formula Weight
    569.63
  • Molecular Formula
    C32H32FN5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (175.55 mM)
  • SMILES
    O=C(NC1=CC=C(F)C(=C1)NC(=O)C=2C=CC=3N=C(C=CC3C2)CN4CCN(CC)CC4)C5=CC=C6OCCOC6=C5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sunder-Plassmann N, et al. Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5. Bioorg Med Chem. 2005 Nov 15;13(22):6094-111.
molnova catalog
related products
  • PU-H71 HCl

    PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.

  • TRC051384

    TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.

  • KNK-437

    An inhibitor of Heat shock protein (HSP) synthesis that dose-dependently inhibits the acquisition of thermotolerance and the induction of various HSPs including HSP105, HSP70, and HSP40 in human colon carcinoma cells.