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1-Ethynylpyrene
CAS No. 34993-56-1
1-Ethynylpyrene( —— )
Catalog No. M28844 CAS No. 34993-56-1
1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 27 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product Name1-Ethynylpyrene
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NoteResearch use only, not for human use.
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Brief Description1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).
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Description1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).(In Vitro):The Ki values of 1-Ethynylpyrene against P450 1A2, and 2B1 is 0.32 and 0.04 μM, respectively.
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In Vitro1-Ethynylpyrene exhibits activity against P450 1A2, and 2B1 with Kis of 0.32 and 0.04 μM, respectively.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetP450
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RecptorLFA-1|ICAM-1|IL-2
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Research Area——
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Indication——
Chemical Information
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CAS Number34993-56-1
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Formula Weight226.278
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Molecular FormulaC18H10
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 9.09 mg/mL (40.17 mM)
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SMILESC#Cc1ccc2ccc3cccc4ccc1c2c34
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tazawa K, Koutsogiannaki S, Chamberlain M, Yuki K. The effect of different anesthetics on tumor cytotoxicity by natural killer cells. Toxicol Lett. 2017 Jan 15;266:23-31.
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