Cart
sales@molnova.com
Eliapixant
CAS No. 1948229-21-7
Eliapixant( BAY 1817080 )
Catalog No. M28734 CAS No. 1948229-21-7
Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 231 | In Stock |
|
| 5MG | 217 | In Stock |
|
| 10MG | 312 | In Stock |
|
| 25MG | 511 | In Stock |
|
| 50MG | 693 | In Stock |
|
| 100MG | 918 | In Stock |
|
| 200MG | 1279 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameEliapixant
-
NoteResearch use only, not for human use.
-
Brief DescriptionEliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
-
DescriptionEliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.(In Vivo):Eliapixant can be used for the research of coughs and diabetes complications.
-
In Vitro——
-
In Vivo——
-
SynonymsBAY 1817080
-
PathwayMembrane Transporter/Ion Channel
-
TargetP2X Receptor
-
RecptorB. subtilis|Antifungal
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1948229-21-7
-
Formula Weight478.49
-
Molecular FormulaC22H21F3N4O3S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 33.33 mg/mL (69.66 mM)
-
SMILESC[C@@H](NC(=O)c1cc(O[C@@H]2CCOC2)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Yao Xinsheng, et al. Cyclic dipeptide constituents from the mangrove fungus Penicillium oxalicum(No.092007). Journal of Shenyang Pharmaceutical University, 2007,24(8) :474-8.
molnova catalog
related products
-
JNJ-55308942
JNJ-55308942 is a novel highly potent P2X7 antagonist with Ki of 1.0 and 6.5 nM for rat and human hP2X7, demonstrates significant activity against a panel of related P2X receptors (P2X1, P2X2, P2X3, P2X2/3, and P2X4; also shows insignificant inhibition of nine CYP isoforms (IC50>15 uM).
-
Brilliant blue G-250
Brilliant Blue G is an antagonist of the P2X7 purinergic receptor.
-
GSK-1482160
GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity.
