Eliapixant( BAY 1817080 )

Catalog No. M28734 CAS No. 1948229-21-7

Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.

Purity : >98% (HPLC)

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Biological Information

Product Name

Eliapixant
Note

Research use only, not for human use.
Brief Description

Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
Description

Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.(In Vivo):Eliapixant can be used for the research of coughs and diabetes complications.
In Vitro

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In Vivo

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Synonyms

BAY 1817080
Pathway

Membrane Transporter/Ion Channel
Target

P2X Receptor
Recptor

B. subtilis|Antifungal
Research Area

——
Indication

——

Chemical Information

CAS Number

1948229-21-7
Formula Weight

478.49
Molecular Formula

C22H21F3N4O3S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 33.33 mg/mL (69.66 mM)
SMILES

C[C@@H](NC(=O)c1cc(O[C@@H]2CCOC2)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Yao Xinsheng, et al. Cyclic dipeptide constituents from the mangrove fungus Penicillium oxalicum(No.092007). Journal of Shenyang Pharmaceutical University, 2007,24(8) :474-8.

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