Stafia-1

CAS No. 2582757-90-0

Stafia-1( —— )

Catalog No. M28612 CAS No. 2582757-90-0

Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 218 In Stock
5MG 187 In Stock
10MG 310 In Stock
25MG 525 In Stock
50MG 740 In Stock
100MG 1014 In Stock
200MG Get Quote In Stock
500MG 2065 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Stafia-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.
  • Description
    Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.
  • In Vitro
    Stafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other STAT family members.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    NOP receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2582757-90-0
  • Formula Weight
    506.44
  • Molecular Formula
    C24H27O10P
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (493.64 mM)
  • SMILES
    COC1=CC(C2=CC(OP(O)(O)=O)=CC(C3=CC(OC)=C(OC)C(OC)=C3)=C2)=CC(OC)=C1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Thomsen C, Hohlweg R. (8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4. 5]dec-3-yl)-acetic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist. Br J Pharmacol. 2000 Nov;131(5):903-8.
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