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LLL3

CAS No. 63972-38-3

LLL3( LLL 3 )

Catalog No. M15430 CAS No. 63972-38-3

LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    LLL3
  • Note
    Research use only, not for human use.
  • Brief Description
    LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor.
  • Description
    LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor, inhibits STAT3-dependent transcriptional and DNA binding activities; also inhibits viability of U87, U373, and U251 glioblastoma cells as well as induces apoptosis of these glioblastoma cell lines; exhibits prolonged survival in U87 glioblastoma tumour-bearing mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    LLL 3
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    63972-38-3
  • Formula Weight
    266.252
  • Molecular Formula
    C16H10O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=C2C=CC=C1O)C3=CC=CC(C(C)=O)=C3C2=O
  • Chemical Name
    1-acetyl-5-hydroxyanthracene-9,10-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fuh B, et al. Br J Cancer. 2009 Jan 13;100(1):106-12. 2. Fossey SL, et al. BMC Cancer. 2009 Mar 10;9:81. 3. Mencalha AL, et al. Cancer Chemother Pharmacol. 2010 May;65(6):1039-46.
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