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Erasin
CAS No. ——
Erasin( —— )
Catalog No. M17028 CAS No. ——
A potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameErasin
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays.
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DescriptionA potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays; induces apoptosis in Erlotinib-resistant lung cancer cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight349.39
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Molecular FormulaC20H19N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(N/N=C/C1=COC2=C(C=C(C(C)(C)C)C=C2)C1=O)C3=CN=CC=C3
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Chemical Name(E)-N'-((6-(tert-butyl)-4-oxo-4H-chromen-3-yl)methylene)nicotinohydrazide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lis C, et al. Sci Rep. 2017 Dec 12;7(1):17390.
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