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TTBK1-IN-2

CAS No. 2765453-51-6

TTBK1-IN-2( N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine )

Catalog No. M28535 CAS No. 2765453-51-6

TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 170 In Stock
5MG 162 In Stock
10MG 239 In Stock
25MG 398 In Stock
50MG 554 In Stock
100MG 742 In Stock
200MG 995 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    TTBK1-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
  • Description
    TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2765453-51-6
  • Formula Weight
    336.77
  • Molecular Formula
    C18H13ClN4O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (148.46 mM)
  • SMILES
    ClC1=CC=C(OC2=CC=C(C=C2)NC=3N=CN=C4NC=CC43)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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