Cart
sales@molnova.com
TTBK1-IN-2
CAS No. 2765453-51-6
TTBK1-IN-2( N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine )
Catalog No. M28535 CAS No. 2765453-51-6
TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 170 | In Stock |
|
| 5MG | 162 | In Stock |
|
| 10MG | 239 | In Stock |
|
| 25MG | 398 | In Stock |
|
| 50MG | 554 | In Stock |
|
| 100MG | 742 | In Stock |
|
| 200MG | 995 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTTBK1-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionTTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
-
DescriptionTTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
-
In Vitro——
-
In Vivo——
-
SynonymsN-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetMicrotubule/Tubulin
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2765453-51-6
-
Formula Weight336.77
-
Molecular FormulaC18H13ClN4O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (148.46 mM)
-
SMILESClC1=CC=C(OC2=CC=C(C=C2)NC=3N=CN=C4NC=CC43)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
Fraxin
Fraxin is a glucoside of fraxetin.
-
Deoxypodophyllotoxin
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities.Deoxypodophyllotoxin (DPT) induced both apoptosis and autophagy via production of mitochondrial reactive oxygen species (ROS).?
-
Lexibulin
An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo.
