TTBK1-IN-2

CAS No. 2765453-51-6

TTBK1-IN-2( N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine )

Catalog No. M28535 CAS No. 2765453-51-6

TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 257 Get Quote
10MG 378 Get Quote
25MG 628 Get Quote
50MG 894 Get Quote
100MG 1197 Get Quote
500MG 2412 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    TTBK1-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
  • Description
    TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2765453-51-6
  • Formula Weight
    336.77
  • Molecular Formula
    C18H13ClN4O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (148.46 mM)
  • SMILES
    ClC1=CC=C(OC2=CC=C(C=C2)NC=3N=CN=C4NC=CC43)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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