Tinoridine

Research use only, not for human use.

Tinoridine is a chemical compound.

Tinoridine is a chemical compound.

Tinoridine (10-100 μM) exerts effect on stability of rat liver and kidney lysosomes, and liver parenchymal cells.Tinoridine (1, 10, and 100 μM; 30 min) inhibits spontaneous release of acid phosphatase from liver lymomoses in vitro.

Tinoridine (100 mg/kg; p.o.; single dose) inhibits CCl4 hepatotoxicity in rats, with a strong control of the CCl4-induced enzyme activities.Tinoridine (100 mg/kg; i.p.; single dose) protects the stability of rat liver and kidney lysosomes in vivo. Animal Model:Male Wistar rats (180-220 g)Dosage:100 mg/kg Administration:Oral gavage; single dose; 1 hour before CCl4 (i.p.; 0.25 mL/kg) treatment Result:Inhibited the CCl4-induced enzyme activities increase of serum glutamic-oxaloacetic transaminase and glutamic-pyruvic transaminase, and also rescued the liver microsomal cytochrome P-450 and glucose-6-phosphatase activities.

ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate

Metabolic Enzyme/Protease

P450

IL Receptor|TNF-α|COX

——

——

24237-54-5

316.42

C17H20N2O2S

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (395.04 mM)

CCOC(=O)c1c(N)sc2CN(Cc3ccccc3)CCc12

——

(-20℃)

With Ice Pack

≥ 2 years