L-Phenylalanine-15N
CAS No. 29700-34-3
L-Phenylalanine-15N( (S)-2-Amino-3-phenylpropionic acid-15N )
Catalog No. M28293 CAS No. 29700-34-3
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
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| 25MG | 86 | Get Quote |
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| 50MG | 133 | Get Quote |
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Biological Information
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Product NameL-Phenylalanine-15N
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NoteResearch use only, not for human use.
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Brief DescriptionL-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM.
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DescriptionL-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) ( K B of 573 μM ) and non-NMDARs , respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals .(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs .
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In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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In Vivo——
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Synonyms(S)-2-Amino-3-phenylpropionic acid-15N
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorTNF-α|PPARγ|inflammation|IL-12|IL-6
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Research Area——
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Indication——
Chemical Information
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CAS Number29700-34-3
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Formula Weight166.18
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Molecular FormulaC9H11NO2
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Purity>98% (HPLC)
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Solubility——
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SMILES[15NH2][C@@H](CC1=CC=CC=C1)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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TPC2-A1-N
TPC2-A1-N is a novel lipophilic, membrane-permeable subtype-selective TPC2 small molecule agonist that activates endogenous TPC2 to moderately increase lysosomal pH in untransfected cells in a time-dependent manner, and can be used to assay the differential function of TPC2 channels in intact cells.
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Mirogabalin
Mirogabalin (DS-5565) is a novel potent, selective ligand of the α2δ subunit of voltage-gated calcium channels with Kd of 13.5/22.7/27.0/47.6 nM for huamn α2δ-1, human α2δ-2, rat α2δ-1 and rat α2δ-2 subunits, respectively.
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Ambocin
Ambocin is a natural product from Pueraria mirifica. Ambocin blocks Ba2+ currents through CaV1.2 channels (IBa1.2) in a concentration-dependent manner and increases IKCa1.1.
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