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TTA-Q6
CAS No. 910484-28-5
TTA-Q6( —— )
Catalog No. M33156 CAS No. 910484-28-5
TTA-Q6, a selective T-type Ca2+ channel antagonist, exhibits potential antitumor and immunomodulatory activities for treating neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cells, thereby inducing intracellular calcium deficiency and endoplasmic reticulum (ER) stress.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 88 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTTA-Q6
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NoteResearch use only, not for human use.
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Brief DescriptionTTA-Q6, a selective T-type Ca2+ channel antagonist, exhibits potential antitumor and immunomodulatory activities for treating neurological disorders by inhibiting the uptake of extracellular calcium ions by tumor cells, thereby inducing intracellular calcium deficiency and endoplasmic reticulum (ER) stress.
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DescriptionTTA-Q6 is a selective T-type Ca2+ channel antagonist, which can be used in the research of neurological disease.
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In VitroTTA-Q6 is a selective T-type Ca2+ channel antagonist, with 14 nM and 590 nM in FLIPR depolarized assaay and FLIPR hyperpolarized assay.
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number910484-28-5
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Formula Weight405.8
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Molecular FormulaC20H15ClF3N3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (308.03 mM; Ultrasonic )
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SMILESFC(F)(F)CN1C(=O)Nc2ccc(Cl)cc2[C@]1(C1CC1)c1ccc(cc1)C#N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Schlegel KA, et al. Discovery and expanded SAR of 4,4-disubstituted quinazolin-2-ones as potent T-type calcium channel antagonists. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5147-52.?
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